While working as a neurosurgeon in Japan, Hiroki Uchikawa dedicated his research to the study of intracranial aneurysms. Using computer simulations, he investigated the hemodynamics of aneurysms, aiming to deepen the understanding of their development, growth, and rupture. Through this research experience, Hiroki noticed the significance of translational research in this field. Currently, his focus has shifted to translational research in intracranial aneurysms, where he employs animal models to identify novel pharmacological targets for the prevention of aneurysm rupture.