| |
Research Grants
The Brain Aneurysm Foundation is proud to offer three $10,000 Research Grants that will be awarded in September 2008 for basic science and translational research projects. The application deadline has been extended until April 25, 2008.
The 2007 Grant Recipients and their research are:
Dr. Jou
Baylor College of Medicine
"Effects of Perianeurysmal Environment and Hemodynamics on Brain Aneurysm Development"
Dr. Jou's research, entitled "Effects of Perianeurysmal Environment and Hemodynamics on Brain Aneurysm Development," will evaluate specific factors that may lead to aneurysm growth by examining arterial blood flow. This research will be conducted using a specific scanning technique, DynaCT, along with a standard imaging tool that can evaluate both the tissue around the brain along with the blood vessels. These tools will enable researchers to measure blood flow in and around the aneurysm to see what factors, including aneurysmal shape and size, and whatever force, if any, may contribute to higher risk of aneurysmal rupture.
Dr. Mocco
University at Buffalo Neurosurgery
"Evaluation of The Hemodynamic Induction of Intracranial Aneurysms"
Dr. Mocco will study the formation of aneurysms resulting from the stress of blood flow on blood vessels in the brain. Dr. Mocco's research, "Evaluation of the Hemodynamic Induction of Intracranial Aneurysms," will use specific techniques to induce chronic blood flow and will examine the impact of increased blood flow on vessel walls and the potential impact on the development of aneurysms.
Cynthia Lynn Sherwin Chair of Research
The Brain Aneurysm Foundation is pleased to announce the establishment of the Cynthia Lynn Sherwin Chair of Research to be awarded in September 2008. The $10,000 research grant, made possible through a generous donation by The Cindy Lynn Sherwin Memorial Foundation, will be focused on the early detection of brain aneurysms.
Tragically, Cynthia Lynn Sherwin suffered a ruptured brain aneurysm and died suddenly at the young age of 33 while training for her first Ironman Triathalon. Her family and friends have established the Cynthia Lynn Sherwin Chair of Research in loving memory of Cindy to help further research in brain aneurysms, so hopefully other families will not experience the same kind of tragedy, losing a loved one at such a young age.
To read more about Cindy's life, please click below.
Go to Cindy's Biography
Familial Intracranial Aneurysm (FIA) Study
The Familial Intracranial Aneurysm (FIA) study is a collaborative effort of physicians from throughout the United States, Canada, Australia, and New Zealand to identify genes that may be important in the development of aneurysms in the blood vessels of the brain. The FIA Study, is the largest study of the genetics of brain aneurysm in the world (currently more than 540 families). The study has made tremendous contributions to our understanding of why and in whom brain aneurysms form. This study of affected families is sponsored by the National Institutes of Health.
To be eligible to participate in this study, families must have two or more affected pairs of siblings (brothers/sisters) or 3 or more family members affected with intracerebral aneurysms. Participants are asked to complete a family history questionnaire and a medical history questionnaire. They also have their blood pressure measured and give a small sample of blood. In addition, certain family members are offered the opportunity to undergo a Magnetic Resonance Angiography MRA (a non-invasive diagnostic test) to look for undiagnosed brain aneurysms.
FIA I enrollment was completed in July 2007. Analysis of the genetic results is on-going and will be released in the spring of 2008. The study investigators have submitted to the National Institutes of Health for a continuation of the grant for an additional five years. This opportunity will allow for the enrollment of 300 additional families and 1200 persons with an intracranial aneurysm but no family history. These additional families and people without a family history will allow the study to replicate the genetic findings of FIA I, and to determine if the genetic findings are also present in people without a family history. You can follow the progress of this very important study, as well as the latest findings at the study website www.FIAStudy.org.
"GIANT" Trial
The Yale University School of Medicine, Department of Neurosurgery is conducting a study on the genetics of intracranial aneurysms called Genetics of Intracranial Aneurysm Trial (GIANT).
Participation is easy and may be done entirely from your home. This study does not require a doctor's visit or an appointment at Yale. Participants will be sent a kit containing everything needed to be part of the study -- clear and concise instructions, a consent form to sign and a special container to provide a saliva sample and a return mailer. No blood draw will be required.
This study is focused on identifying genes contributing to the formation and bleeding of brain aneurysms. The principal investigator, Dr Murat Gunel, and his team, have been conducting research into the causes of aneurysms for over a decade. The study is conducted under the auspices of the Yale University School of Medicine's Human Investigation Committee. This study involves participants from both Finland and the US.
For further information on this study please contact Anita Farhi, RN at giant@yale.edu or 1-800-575-9253.
Other Current Research Studies
For more information on clinical trials in your area, please visit clinical trials
|
|
|
